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Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling

During development, looping of an enhancer to a promoter is frequently observed in conjunction with temporal and tissue-specific transcriptional activation. The chromatin insulator-associated protein Alan Shepard (Shep) promotes Drosophila post-mitotic neuronal remodeling by repressing transcription...

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Detalles Bibliográficos
Autores principales: Chen, Dahong, McManus, Catherine E., Radmanesh, Behram, Matzat, Leah H., Lei, Elissa P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568962/
https://www.ncbi.nlm.nih.gov/pubmed/34737269
http://dx.doi.org/10.1038/s41467-021-26628-7