SPINDOC binds PARP1 to facilitate PARylation

SPINDOC is tightly associated with the histone H3K4me3 effector protein SPIN1. To gain a better understanding of the biological roles of SPINDOC, we identified its interacting proteins. Unexpectedly, SPINDOC forms two mutually exclusive protein complexes, one with SPIN1 and the other with PARP1. Con...

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Detalles Bibliográficos
Autores principales: Yang, Fen, Chen, Jianji, Liu, Bin, Gao, Guozhen, Sebastian, Manu, Jeter, Collene, Shen, Jianjun, Person, Maria D., Bedford, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568969/
https://www.ncbi.nlm.nih.gov/pubmed/34737271
http://dx.doi.org/10.1038/s41467-021-26588-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568969/
https://www.ncbi.nlm.nih.gov/pubmed/34737271
http://dx.doi.org/10.1038/s41467-021-26588-y

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