Mitochondrial-nuclear cross-talk in the human brain is modulated by cell type and perturbed in neurodegenerative disease

Mitochondrial dysfunction contributes to the pathogenesis of many neurodegenerative diseases. The mitochondrial genome encodes core respiratory chain proteins, but the vast majority of mitochondrial proteins are nuclear-encoded, making interactions between the two genomes vital for cell function. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Fairbrother-Browne, Aine, Ali, Aminah T., Reynolds, Regina H., Garcia-Ruiz, Sonia, Zhang, David, Chen, Zhongbo, Ryten, Mina, Hodgkinson, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569145/
https://www.ncbi.nlm.nih.gov/pubmed/34737414
http://dx.doi.org/10.1038/s42003-021-02792-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569145/
https://www.ncbi.nlm.nih.gov/pubmed/34737414
http://dx.doi.org/10.1038/s42003-021-02792-w

Ejemplares similares