Cargando…

Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart

Cardiac morphogenesis relies on intricate intercellular signaling. Altered signaling impacts cardiac function and is detrimental to embryonic survival. Here we report an unexpected regulatory role of the desmosomal cell adhesion molecule desmoglein 2 (Dsg2) on murine heart development. A large perce...

Descripción completa

Detalles Bibliográficos
Autores principales: Moazzen, Hoda, Venger, Kateryna, Kant, Sebastian, Leube, Rudolf E., Krusche, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569146/
https://www.ncbi.nlm.nih.gov/pubmed/34737300
http://dx.doi.org/10.1038/s41598-021-00996-y