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Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart
Cardiac morphogenesis relies on intricate intercellular signaling. Altered signaling impacts cardiac function and is detrimental to embryonic survival. Here we report an unexpected regulatory role of the desmosomal cell adhesion molecule desmoglein 2 (Dsg2) on murine heart development. A large perce...
Autores principales: | Moazzen, Hoda, Venger, Kateryna, Kant, Sebastian, Leube, Rudolf E., Krusche, Claudia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569146/ https://www.ncbi.nlm.nih.gov/pubmed/34737300 http://dx.doi.org/10.1038/s41598-021-00996-y |
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