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MOFs-based nanoagent enables dual mitochondrial damage in synergistic antitumor therapy via oxidative stress and calcium overload

Targeting subcellular organelle with multilevel damage has shown great promise for antitumor therapy. Here, we report a core-shell type of nanoagent with iron (III) carboxylate metal-organic frameworks (MOFs) as shell while upconversion nanoparticles (UCNPs) as core, which enables near-infrared (NIR...

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Detalles Bibliográficos
Autores principales: Bao, Weier, Liu, Ming, Meng, Jiaqi, Liu, Siyuan, Wang, Shuang, Jia, Rongrong, Wang, Yugang, Ma, Guanghui, Wei, Wei, Tian, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569165/
https://www.ncbi.nlm.nih.gov/pubmed/34737274
http://dx.doi.org/10.1038/s41467-021-26655-4