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Lactate activates hypothalamic POMC neurons by intercellular signaling

Previous studies indicate that the activity of hypothalamic POMC neurons can be regulated by glucose via intracellular mechanisms, but its regulation by lactate is poorly understood. In addition to its energetic role, lactate acts as a signaling molecule. In this study, we evaluated the function and...

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Detalles Bibliográficos
Autores principales: Órdenes, P., Villar, P. S., Tarifeño-Saldivia, E., Salgado, M., Elizondo-Vega, R., Araneda, Ricardo C., García-Robles, María A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569171/
https://www.ncbi.nlm.nih.gov/pubmed/34737351
http://dx.doi.org/10.1038/s41598-021-00947-7