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Genome Mining-Based Discovery of Blenny Fish-Derived Peptides Targeting the Mouse κ-Opioid Receptor

Over the past years, peptides have attracted increasing interest for G protein-coupled receptor (GPCR) drug discovery and development. Peptides occupy a unique chemical space that is not easily accessible for small molecules and antibodies and provide advantages over these ligand classes such as low...

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Detalles Bibliográficos
Autores principales: Muratspahić, Edin, Retzl, Bernhard, Duerrauer, Leopold, Freissmuth, Michael, Becker, Christian F. W., Gruber, Christian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569185/
https://www.ncbi.nlm.nih.gov/pubmed/34744752
http://dx.doi.org/10.3389/fphar.2021.773029