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Genome Mining-Based Discovery of Blenny Fish-Derived Peptides Targeting the Mouse κ-Opioid Receptor
Over the past years, peptides have attracted increasing interest for G protein-coupled receptor (GPCR) drug discovery and development. Peptides occupy a unique chemical space that is not easily accessible for small molecules and antibodies and provide advantages over these ligand classes such as low...
Autores principales: | Muratspahić, Edin, Retzl, Bernhard, Duerrauer, Leopold, Freissmuth, Michael, Becker, Christian F. W., Gruber, Christian W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569185/ https://www.ncbi.nlm.nih.gov/pubmed/34744752 http://dx.doi.org/10.3389/fphar.2021.773029 |
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