Cargando…

Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data

Intratumour heterogeneity provides tumours with the ability to adapt and acquire treatment resistance. The development of more effective and personalised treatments for cancers, therefore, requires accurate characterisation of the clonal architecture of tumours, enabling evolutionary dynamics to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanner, Georgette, Westhead, David R., Droop, Alastair, Stead, Lucy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569188/
https://www.ncbi.nlm.nih.gov/pubmed/34737285
http://dx.doi.org/10.1038/s41467-021-26698-7