Cargando…
Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data
Intratumour heterogeneity provides tumours with the ability to adapt and acquire treatment resistance. The development of more effective and personalised treatments for cancers, therefore, requires accurate characterisation of the clonal architecture of tumours, enabling evolutionary dynamics to be...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569188/ https://www.ncbi.nlm.nih.gov/pubmed/34737285 http://dx.doi.org/10.1038/s41467-021-26698-7 |