Thrap3 promotes R-loop resolution via interaction with methylated DDX5

Transcription-replication conflicts lead to DNA damage and genomic instability, which are closely related to human diseases. A major source of these conflicts is the formation of R-loops, which consist of an RNA-DNA hybrid and a displaced single-stranded DNA. Although these structures have been stud...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Je, Eom, Hye-jin, Kim, Hongtae, Myung, Kyungjae, Kwon, Hyug Moo, Choi, Jang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569202/
https://www.ncbi.nlm.nih.gov/pubmed/34697388
http://dx.doi.org/10.1038/s12276-021-00689-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569202/
https://www.ncbi.nlm.nih.gov/pubmed/34697388
http://dx.doi.org/10.1038/s12276-021-00689-6

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