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Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis

Ramucirumab is the first FDA-approved monotherapy for advanced gastric cancer. In this study, Ramucirumab (Ab) is attached to gold nanoparticles to enhance uptake efficiency. Gold nanoparticles can induce direct cytotoxic effects to cancer cells in the presence of Ab, while individual Ab or gold nan...

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Detalles Bibliográficos
Autores principales: Fan, Linyang, Wang, Weizhi, Wang, Zihua, Zhao, Minzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569206/
https://www.ncbi.nlm.nih.gov/pubmed/34737259
http://dx.doi.org/10.1038/s41467-021-26694-x