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Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma

Cryoablation in combination with immune checkpoint therapy was previously reported to improve anti-tumor immune responses in pre-clinical studies. Here we report a pilot study of anti-CTLA-4 (tremelimumab) with (n = 15) or without (n = 14) cryoablation in patients with metastatic renal cell carcinom...

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Detalles Bibliográficos
Autores principales: Campbell, Matthew T., Matin, Surena F., Tam, Alda L., Sheth, Rahul A., Ahrar, Kamran, Tidwell, Rebecca S., Rao, Priya, Karam, Jose A., Wood, Christopher G., Tannir, Nizar M., Jonasch, Eric, Gao, Jianjun, Zurita, Amado J., Shah, Amishi Y., Jindal, Sonali, Duan, Fei, Basu, Sreyashi, Chen, Hong, Espejo, Alexsandra B., Allison, James P., Yadav, Shalini S., Sharma, Padmanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569213/
https://www.ncbi.nlm.nih.gov/pubmed/34737281
http://dx.doi.org/10.1038/s41467-021-26415-4