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Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation

Although lung cancer is the leading cause of cancer-related deaths worldwide and KRAS is the most frequently mutated oncogene in lung cancer cases, the mechanism by which KRAS mutation drives lung cancer has not been fully elucidated. Here, we report that the expression levels of leukotriene B(4) re...

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Detalles Bibliográficos
Autores principales: Jang, Jae-Hyun, Park, Donghwan, Park, Guen-soo, Kwak, Dong-Wook, Park, JaeIn, Yu, Dae-Yeul, You, Hye Jin, Kim, Jae-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569214/
https://www.ncbi.nlm.nih.gov/pubmed/34635780
http://dx.doi.org/10.1038/s12276-021-00682-z