p-STAT3 is a PDC-E2 interacting partner in human cholangiocytes and hepatocytes with potential pathobiological implications

The E2 component of the mitochondrial pyruvate dehydrogenase complex (PDC) is the key autoantigen in primary biliary cholangitis (PBC) and STAT3 is an inflammatory modulator that participates in the pathogenesis of many liver diseases. This study investigated whether PDC-E2 interacts with STAT3 in h...

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Detalles Bibliográficos
Autores principales: Kilanczyk, Ewa, Banales, Jesus M., Jurewicz, Ewelina, Milkiewicz, Piotr, Milkiewicz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569217/
https://www.ncbi.nlm.nih.gov/pubmed/34737337
http://dx.doi.org/10.1038/s41598-021-01060-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569217/
https://www.ncbi.nlm.nih.gov/pubmed/34737337
http://dx.doi.org/10.1038/s41598-021-01060-5

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