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p-STAT3 is a PDC-E2 interacting partner in human cholangiocytes and hepatocytes with potential pathobiological implications
The E2 component of the mitochondrial pyruvate dehydrogenase complex (PDC) is the key autoantigen in primary biliary cholangitis (PBC) and STAT3 is an inflammatory modulator that participates in the pathogenesis of many liver diseases. This study investigated whether PDC-E2 interacts with STAT3 in h...
Autores principales: | Kilanczyk, Ewa, Banales, Jesus M., Jurewicz, Ewelina, Milkiewicz, Piotr, Milkiewicz, Malgorzata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569217/ https://www.ncbi.nlm.nih.gov/pubmed/34737337 http://dx.doi.org/10.1038/s41598-021-01060-5 |
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