Chemically Synthesized Alcaligenes Lipid A as an Adjuvant to Augment Immune Responses to Haemophilus Influenzae Type B Conjugate Vaccine

We previously identified Alcaligenes spp. as a commensal bacterium that resides in lymphoid tissues, including Peyer’s patches. We found that Alcaligenes-derived lipopolysaccharide acted as a weak agonist of Toll-like receptor four due to the unique structure of lipid A, which lies in the core of li...

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Detalles Bibliográficos
Autores principales: Liu, Zilai, Hosomi, Koji, Shimoyama, Atsushi, Yoshii, Ken, Sun, Xiao, Lan, Huangwenxian, Wang, Yunru, Yamaura, Haruki, Kenneth, Davie, Saika, Azusa, Nagatake, Takahiro, Kiyono, Hiroshi, Fukase, Koichi, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569242/
https://www.ncbi.nlm.nih.gov/pubmed/34744743
http://dx.doi.org/10.3389/fphar.2021.763657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569242/
https://www.ncbi.nlm.nih.gov/pubmed/34744743
http://dx.doi.org/10.3389/fphar.2021.763657

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