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Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop

BACKGROUND: The underlying mechanisms of the potential tumor-suppressive effects of ginsenoside Rh2 are complex. N6-methyladenosine (m6A) RNA methylation is usually dysregulated in cancer. This study explored the regulatory effect of ginsenoside Rh2 on m6A RNA methylation in cancer. Methods: m6A RNA...

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Detalles Bibliográficos
Autores principales: Hu, Chunmei, Yang, Linhan, Wang, Yi, Zhou, Shijie, Luo, Jing, Gu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569326/
https://www.ncbi.nlm.nih.gov/pubmed/34764728
http://dx.doi.org/10.1016/j.jgr.2021.05.004