Endoplasmic reticulum stress promotes sorafenib resistance via miR-188-5p/hnRNPA2B1-mediated upregulation of PKM2 in hepatocellular carcinoma

Emerging evidence has shown that endoplasmic reticulum (ER) stress promotes sorafenib resistance in hepatocellular carcinoma (HCC). However, the underlying mechanisms are poorly understood. The purpose of this study was to explore the mechanism by which ER stress promotes sorafenib resistance in HCC...

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Detalles Bibliográficos
Autores principales: Zhou, Bei, Lu, Donghui, Wang, Anqi, Cui, Jie, Zhang, Li, Li, Jian, Fan, Lulu, Wei, Wei, Liu, Jiatao, Sun, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569435/
https://www.ncbi.nlm.nih.gov/pubmed/34786210
http://dx.doi.org/10.1016/j.omtn.2021.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569435/
https://www.ncbi.nlm.nih.gov/pubmed/34786210
http://dx.doi.org/10.1016/j.omtn.2021.09.014

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