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Atractylenolide-III suppresses lipopolysaccharide-induced inflammation via downregulation of toll-like receptor 4 in mouse microglia

Atractylenolide-III (AIII), a sesquiterpene compound isolated from the rhizome of Atractylodes macrocephala, has been reported to have anti-inflammatory effects in the peripheral organs. However, its effects on brain inflammation remain elusive. The present study investigated the effects of AIII on...

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Detalles Bibliográficos
Autores principales: Novianti, Ela, Katsuura, Goro, Kawamura, Namiko, Asakawa, Akihiro, Inui, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569437/
https://www.ncbi.nlm.nih.gov/pubmed/34765767
http://dx.doi.org/10.1016/j.heliyon.2021.e08269