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Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71(+) Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model

The CD71(+) erythroid progenitor cells (CECs) exhibit distinctive immunosuppressive properties and regulate antitumor immunity to enable tumor growth. We presented a novel and non-invasive approach to improving immunity by targeting the splenic CECs via sonoporation generated by ultrasound-targeted...

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Detalles Bibliográficos
Autores principales: Tan, Xi, Yi, Cuo, Zhang, Yi, Tang, Najiao, Xu, Yali, Liu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569521/
https://www.ncbi.nlm.nih.gov/pubmed/34746009
http://dx.doi.org/10.3389/fonc.2021.768222