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Structural determinants of the integrin transmembrane domain required for bidirectional signal transmission across the cell membrane
Studying the tight activity regulation of platelet-specific integrin α(IIb)β(3) is foundational and paramount to our understanding of integrin structure and activation. α(IIb)β(3) is essential for the aggregation and adhesion function of platelets in hemostasis and thrombosis. Structural and mutagen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569584/ https://www.ncbi.nlm.nih.gov/pubmed/34678312 http://dx.doi.org/10.1016/j.jbc.2021.101318 |