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Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis

Neddylation is a posttranslational modification that attaches ubiquitin-like protein Nedd8 to protein targets via Nedd8-specific E1-E2-E3 enzymes and modulates many important biological processes. Nedd8 attaches to a lysine residue of a substrate, not for degradation, but for modulation of substrate...

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Detalles Bibliográficos
Autores principales: Du, Meng-ge, Liu, Fan, Chang, Yan, Tong, Shuai, Liu, Wei, Chen, Yu-jiao, Xie, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569593/
https://www.ncbi.nlm.nih.gov/pubmed/34662580
http://dx.doi.org/10.1016/j.jbc.2021.101307