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Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D(2) Synthase as a Multifunctional Lipocalin
Lipocalin-type prostaglandin (PG) D(2) synthase (L-PGDS) catalyzes the isomerization of PGH(2), a common precursor of the two series of PGs, to produce PGD(2). PGD(2) stimulates three distinct types of G protein-coupled receptors: (1) D type of prostanoid (DP) receptors involved in the regulation of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569824/ https://www.ncbi.nlm.nih.gov/pubmed/34744762 http://dx.doi.org/10.3389/fphys.2021.718002 |