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Safety of sildenafil in extremely premature infants: a phase I trial

OBJECTIVE: To characterize the safety of sildenafil in premature infants. STUDY DESIGN: A phase I, open-label trial of sildenafil in premature infants receiving sildenafil per usual clinical care (cohort 1) or receiving a single IV dose of sildenafil (cohort 2). Safety was evaluated based on adverse...

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Detalles Bibliográficos
Autores principales: Jackson, Wesley, Gonzalez, Daniel, Smith, P. Brian, Ambalavanan, Namasivayam, Atz, Andrew M., Sokol, Gregory M., Hornik, Chi D., Stewart, Dan, Mundakel, Gratias, Poindexter, Brenda B., Ahlfeld, Shawn K., Mills, Mary, Cohen-Wolkowiez, Michael, Martz, Karen, Hornik, Christoph P., Laughon, Matthew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569839/
https://www.ncbi.nlm.nih.gov/pubmed/34741102
http://dx.doi.org/10.1038/s41372-021-01261-w