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Detection of granzyme B in CD3-positive cells infiltrated in lesional skin of a dog with erythema multiforme associated with zonisamide

In human erythema multiforme (EM), cytotoxic T lymphocytes (CTLs) play an essential role in the pathogenesis. In canine EM, immunohistochemical staining with anti-CD8 antibody using frozen sections has shown the involvement of CTLs; however, CTL infiltration has never been quantitatively analyzed. W...

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Detalles Bibliográficos
Autores principales: TANAKA, Nana, KANEI, Toshitaka, IWATA, Munetaka, KAWABE, Mifumi, KAMISHINA, Hiroaki, MURAKAMI, Mami, SAKAI, Hiroki, MAEDA, Sadatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569875/
https://www.ncbi.nlm.nih.gov/pubmed/34433730
http://dx.doi.org/10.1292/jvms.21-0146