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Effects of dapagliflozin in combination with insulin on cytochrome P450 activities in a diabetes type 1 rat model
Previous studies reported that diabetes alters the activities of hepatic cytochrome P450 (CYP) enzymes, which, in turn, affects the disposition of some drugs. We herein examined and compared the effects of the combination of dapagliflozin with a low insulin dose, a full dose of insulin alone, and da...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569876/ https://www.ncbi.nlm.nih.gov/pubmed/34483187 http://dx.doi.org/10.1292/jvms.21-0249 |