Functions of the CSB Protein at Topoisomerase 2 Inhibitors-Induced DNA Lesions

Topoisomerase 2 (TOP2) inhibitors are drugs widely used in the treatment of different types of cancer. Processing of their induced-lesions create double-strand breaks (DSBs) in the DNA, which is the main toxic mechanism of topoisomerase inhibitors to kill cancer cells. It was established that the Nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Busatto, Franciele Faccio, Mersaoui, Sofiane Y., Sun, Yilun, Pommier, Yves, Masson, Jean-Yves, Saffi, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569893/
https://www.ncbi.nlm.nih.gov/pubmed/34746125
http://dx.doi.org/10.3389/fcell.2021.727836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569893/
https://www.ncbi.nlm.nih.gov/pubmed/34746125
http://dx.doi.org/10.3389/fcell.2021.727836

Ejemplares similares