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Monocytic THP-1 cells diverge significantly from their primary counterparts: a comparative examination of the chromosomal conformations and transcriptomes

Immortalized cell lines have long been used as model systems to systematically investigate biological processes under controlled and reproducible conditions, providing insights that have greatly advanced cellular biology and medical sciences. Recently, the widely used monocytic leukemia cell line, T...

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Detalles Bibliográficos
Autores principales: Liu, Yulong, Li, Hua, Czajkowsky, Daniel M., Shao, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569982/
https://www.ncbi.nlm.nih.gov/pubmed/34740370
http://dx.doi.org/10.1186/s41065-021-00205-w