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Lnc-RP11-536 K7.3/SOX2/HIF-1α signaling axis regulates oxaliplatin resistance in patient-derived colorectal cancer organoids

BACKGROUND: Resistance to oxaliplatin is a major obstacle for the management of locally advanced and metastatic colon cancer (CC). Although long noncoding RNAs (lncRNAs) play key roles in CC, the relationships between lncRNAs and resistance to oxaliplatin have been poorly understood yet. METHODS: Ch...

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Detalles Bibliográficos
Autores principales: Li, Qingguo, Sun, Huizhen, Luo, Dakui, Gan, Lu, Mo, Shaobo, Dai, Weixing, Liang, Lei, Yang, Yufei, Xu, Midie, Li, Jing, Zheng, Peiyong, Li, Xinxiang, Li, Yan, Wang, Ziliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570024/
https://www.ncbi.nlm.nih.gov/pubmed/34740372
http://dx.doi.org/10.1186/s13046-021-02143-x