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Differential p16 expression levels in the liver, hepatocytes and hepatocellular cell lines
BACKGROUND: One of the most frequently deleted genes in cancer is CDKN2A encoding p16. This protein is often overexpressed in senescent cells, while its suppression can bypass the oncogene-induced senescence to enable transformation and tumorigenesis. The roles of the protein p16 are recently being...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570159/ https://www.ncbi.nlm.nih.gov/pubmed/34760375 http://dx.doi.org/10.7717/peerj.12358 |