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Phylogenetic and Ancestral Sequence Reconstruction of SARS-CoV-2 Reveals Latent Capacity to Bind Human ACE2 Receptor

SARS-CoV-2 is a unique event, having emerged suddenly as a highly infectious viral pathogen for human populations. Previous phylogenetic analyses show its closest known evolutionary relative to be a virus detected in bats (RaTG13), with a common assumption that SARS-CoV-2 evolved from a zoonotic anc...

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Detalles Bibliográficos
Autores principales: Brintnell, Erin, Gupta, Mehul, Anderson, Dave W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570237/
https://www.ncbi.nlm.nih.gov/pubmed/34739551
http://dx.doi.org/10.1007/s00239-021-10034-0