Cargando…

Phylogenetic and Ancestral Sequence Reconstruction of SARS-CoV-2 Reveals Latent Capacity to Bind Human ACE2 Receptor

SARS-CoV-2 is a unique event, having emerged suddenly as a highly infectious viral pathogen for human populations. Previous phylogenetic analyses show its closest known evolutionary relative to be a virus detected in bats (RaTG13), with a common assumption that SARS-CoV-2 evolved from a zoonotic anc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brintnell, Erin, Gupta, Mehul, Anderson, Dave W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570237/ https://www.ncbi.nlm.nih.gov/pubmed/34739551 http://dx.doi.org/10.1007/s00239-021-10034-0

Ejemplares similares

ACE2 binding is an ancestral and evolvable trait of sarbecoviruses
por: Starr, Tyler N., et al.
Publicado: (2022)

Robustness of Ancestral Sequence Reconstruction to Phylogenetic Uncertainty
por: Hanson-Smith, Victor, et al.
Publicado: (2010)

Binding of SARS-COV-2 (COVID-19) and SARS-COV to human ACE2: Identifying binding sites and consequences on ACE2 stiffness
por: Faisal, H.M. Nasrullah, et al.
Publicado: (2021)

The probability distribution of the ancestral population size conditioned on the reconstructed phylogenetic tree with occurrence data
por: Manceau, Marc, et al.
Publicado: (2021)

Permissive omicron breakthrough infections in individuals with binding or neutralizing antibodies to ancestral SARS-CoV-2
por: Williams, Erin, et al.
Publicado: (2022)

Phylogenetic Reconstruction and Functional Characterization of the Ancestral Nef Protein of Primate Lentiviruses
por: Olabode, Abayomi S, et al.
Publicado: (2023)

Ancestral Reconstruction
por: Joy, Jeffrey B., et al.
Publicado: (2016)

Karyotype, evolution and phylogenetic reconstruction in Micronycterinae bats with implications for the ancestral karyotype of Phyllostomidae
por: Benathar, T. C. M., et al.
Publicado: (2019)

The molecular basis for SARS-CoV-2 binding to dog ACE2
por: Zhang, Zengyuan, et al.
Publicado: (2021)

SARS-CoV-2 spike and ACE2 entanglement-like binding
por: Pregnolato, Massimo, et al.
Publicado: (2023)

Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
por: Yang, Jinsung, et al.
Publicado: (2020)

Revealing the Mechanism of SARS-CoV-2 Spike Protein Binding With ACE2
Publicado: (2020)

Identifying compounds that prevent the binding of the SARS-CoV-2 S-protein to ACE2
por: Benítez-Cardoza, Claudia Guadalupe, et al.
Publicado: (2021)

Cross-species binding spectrum of ACE2 to SARS-CoV-2 RBD
por: Liao, Xihao, et al.
Publicado: (2022)

Mechanism and evolution of human ACE2 binding by SARS-CoV-2 spike
por: Wrobel, Antoni G.
Publicado: (2023)

Exploring the disruption of SARS-CoV-2 RBD binding to hACE2
por: Carter, Camryn, et al.
Publicado: (2023)

Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
por: Rossnes, Roald, et al.
Publicado: (2005)

Comparative docking studies to understand the binding affinity of nicotine with soluble ACE2 (sACE2)-SARS-CoV-2 complex over sACE2
por: C., Selvaa Kumar, et al.
Publicado: (2020)

Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding
por: Ghosh, Arunava, et al.
Publicado: (2021)

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19
por: Zhang, Si, et al.
Publicado: (2020)

Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
por: Mehdipour, Ahmad Reza, et al.
Publicado: (2021)

Perturbation of ACE2 Structural Ensembles by SARS-CoV-2 Spike Protein Binding
por: Uyar, Arzu, et al.
Publicado: (2021)

SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged with glycans
por: Huang, Yihan, et al.
Publicado: (2022)

Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding
por: Yang, Li Jun, et al.
Publicado: (2021)

Screened antipsychotic drugs inhibit SARS-CoV-2 binding with ACE2 in vitro
por: Lu, Jiayu, et al.
Publicado: (2021)

Identifying Hotspots in Binding of SARS-CoV-2 Spike Glycoprotein and Human ACE2
por: Mendis, Jenny, et al.
Publicado: (2021)

SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET
por: Cecon, Erika, et al.
Publicado: (2022)

Inferring the stabilization effects of SARS-CoV-2 variants on the binding with ACE2 receptor
por: Miotto, Mattia, et al.
Publicado: (2022)

Multiformin-Type Azaphilones Prevent SARS-CoV-2 Binding to ACE2 Receptor
por: Jansen-Olliges, Linda, et al.
Publicado: (2022)

Modelling SARS-CoV-2 spike-protein mutation effects on ACE2 binding
por: Thakur, Shivani, et al.
Publicado: (2023)

High-resolution and Deep Phylogenetic Reconstruction of Ancestral States from Large Transcriptomic Data Sets
por: Mutte, Sumanth Kumar, et al.
Publicado: (2020)

Taxonomy, Phylogenetic and Ancestral Area Reconstruction in Phyllachora, with Four Novel Species from Northwestern China
por: Li, Jin-Chen, et al.
Publicado: (2022)

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions
por: Day, Christopher J., et al.
Publicado: (2021)

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2
por: Wu, Lili, et al.
Publicado: (2020)

Arthropod Ectoparasites Have Potential to Bind SARS-CoV-2 via ACE
por: Lam, Su Datt, et al.
Publicado: (2021)

Cross-protection and cross-neutralization capacity of ancestral and VOC-matched SARS-CoV-2 adenoviral vector-based vaccines
por: Vinzón, Sabrina E., et al.
Publicado: (2023)

Factors that Affect the Binding of the N-Terminal Helix of Human ACE2 to Spike Protein of SARS-CoV2
por: Das, Anirban, et al.
Publicado: (2021)

Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2
por: Francesconi, Oscar, et al.
Publicado: (2022)

Does SARS-CoV-2 Bind to Human ACE2 More Strongly Than Does SARS-CoV?
por: Nguyen, Hoang Linh, et al.
Publicado: (2020)

Spike Proteins of SARS-CoV and SARS-CoV-2 Utilize Different Mechanisms to Bind With Human ACE2
por: Xie, Yixin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8a6tohddfno9770rmm4068n4sq