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Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage

Excessive UV-B exposure is well known to be a risk factor for corneal phototoxicity including direct DNA damage and disturbances in the antioxidant balance. Here, we showed a successful synthesis of a water-soluble and biocompatible small molecule DHPM 1 with dihydropyrimidinthione skeleton, which c...

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Detalles Bibliográficos
Autores principales: Du, Enming, Pu, Guojuan, He, Siyu, Qin, Fangyuan, Wang, Yange, Wang, Gang, Song, Zongming, Zhang, Junjie, Tao, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570246/
https://www.ncbi.nlm.nih.gov/pubmed/34744716
http://dx.doi.org/10.3389/fphar.2021.732833