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The Donnan-dominated resting state of skeletal muscle fibers contributes to resilience and longevity in dystrophic fibers
Duchenne muscular dystrophy (DMD) is an X-linked dystrophin-minus muscle-wasting disease. Ion homeostasis in skeletal muscle fibers underperforms as DMD progresses. But though DMD renders these excitable cells intolerant of exertion, sodium overloaded, depolarized, and spontaneously contractile, the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570295/ https://www.ncbi.nlm.nih.gov/pubmed/34731883 http://dx.doi.org/10.1085/jgp.202112914 |