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The Donnan-dominated resting state of skeletal muscle fibers contributes to resilience and longevity in dystrophic fibers

Duchenne muscular dystrophy (DMD) is an X-linked dystrophin-minus muscle-wasting disease. Ion homeostasis in skeletal muscle fibers underperforms as DMD progresses. But though DMD renders these excitable cells intolerant of exertion, sodium overloaded, depolarized, and spontaneously contractile, the...

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Detalles Bibliográficos
Autores principales: Morris, Catherine E., Wheeler, Joshua J., Joos, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570295/
https://www.ncbi.nlm.nih.gov/pubmed/34731883
http://dx.doi.org/10.1085/jgp.202112914

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