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Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice

Idiopathic pulmonary fibrosis (IPF) is characterized by fibrotic change in alveolar epithelial cells and leads to the irreversible deterioration of pulmonary function. Transforming growth factor-beta 1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) in type 2 lung epithelial cells contribut...

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Detalles Bibliográficos
Autores principales: Chang, Kai-Wei, Zhang, Xiang, Lin, Shih-Chao, Lin, Yu-Chao, Li, Chia-Hsiang, Akhrymuk, Ivan, Lin, Sheng-Hao, Lin, Chi-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570326/
https://www.ncbi.nlm.nih.gov/pubmed/34681813
http://dx.doi.org/10.3390/ijms222011152