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Accelerating drug repurposing for COVID-19 treatment by modeling mechanisms of action using cell image features and machine learning

The novel coronavirus disease, COVID-19, has rapidly spread worldwide. Developing methods to identify the therapeutic activity of drugs based on phenotypic data can improve the efficiency of drug development. Here, a state-of-the-art machine-learning method was used to identify drug mechanism of act...

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Detalles Bibliográficos
Autores principales: Han, Lu, Shan, Guangcun, Chu, Bingfeng, Wang, Hongyu, Wang, Zhongjian, Gao, Shengqiao, Zhou, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570398/
https://www.ncbi.nlm.nih.gov/pubmed/34777628
http://dx.doi.org/10.1007/s11571-021-09727-5