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Proteomic characterization of GSK3β knockout shows altered cell adhesion and metabolic pathway utilisation in colorectal cancer cells

Glycogen-specific kinase (GSK3β) is an integral regulator of the Wnt signalling pathway as well as many other diverse signalling pathways and processes. Dys-regulation of GSK3β is implicated in many different pathologies, including neurodegenerative disorders as well as many different tumour types....

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Detalles Bibliográficos
Autores principales: Bowler-Barnett, Emily, Martinez-Garcia, Francisco D., Sherwood, Matthew, Aleidan, Ahood, John, Steve, Weston, Sara, Wang, Yihua, Divecha, Nullin, Skipp, Paul, Ewing, Rob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570494/
https://www.ncbi.nlm.nih.gov/pubmed/34739494
http://dx.doi.org/10.1371/journal.pone.0246707