Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx

Human Immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) succeed to evade host immune defenses by using their viral auxiliary proteins to antagonize host restriction factors. HIV-2/SIVsmm Vpx is known for degrading SAMHD1, a factor impeding the reverse transcription. More recently, Vpx was also...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Michaël M., Matkovic, Roy, Larrous, Pauline, Morel, Marina, Lasserre, Angélique, Vauthier, Virginie, Margottin-Goguet, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570500/
https://www.ncbi.nlm.nih.gov/pubmed/34699574
http://dx.doi.org/10.1371/journal.ppat.1009609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570500/
https://www.ncbi.nlm.nih.gov/pubmed/34699574
http://dx.doi.org/10.1371/journal.ppat.1009609

Ejemplares similares