Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach

Large-scale genomic alterations play an important role in disease, gene expression, and chromosome evolution. Optical DNA mapping (ODM), commonly categorized into sparsely-labelled ODM and densely-labelled ODM, provides sequence-specific continuous intensity profiles (DNA barcodes) along single DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Dvirnas, Albertas, Stewart, Callum, Müller, Vilhelm, Bikkarolla, Santosh Kumar, Frykholm, Karolin, Sandegren, Linus, Kristiansson, Erik, Westerlund, Fredrik, Ambjörnsson, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570516/
https://www.ncbi.nlm.nih.gov/pubmed/34739528
http://dx.doi.org/10.1371/journal.pone.0259670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570516/
https://www.ncbi.nlm.nih.gov/pubmed/34739528
http://dx.doi.org/10.1371/journal.pone.0259670

Ejemplares similares