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Detection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach

Large-scale genomic alterations play an important role in disease, gene expression, and chromosome evolution. Optical DNA mapping (ODM), commonly categorized into sparsely-labelled ODM and densely-labelled ODM, provides sequence-specific continuous intensity profiles (DNA barcodes) along single DNA...

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Detalles Bibliográficos
Autores principales:	Dvirnas, Albertas, Stewart, Callum, Müller, Vilhelm, Bikkarolla, Santosh Kumar, Frykholm, Karolin, Sandegren, Linus, Kristiansson, Erik, Westerlund, Fredrik, Ambjörnsson, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570516/ https://www.ncbi.nlm.nih.gov/pubmed/34739528 http://dx.doi.org/10.1371/journal.pone.0259670

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