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Clathrin-coated structures support 3D directed migration through local force transmission

Migrating cells navigate in complex environments through sensing and interpreting biochemical and/or mechanical cues. Here, we report that recently identified tubular clathrin/AP-2 lattices (TCALs), a subset of clathrin-coated structures (CCSs) that pinch collagen fibers, mechanically control direct...

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Detalles Bibliográficos
Autores principales: Bresteau, Enzo, Elkhatib, Nadia, Baschieri, Francesco, Bellec, Karen, Guérin, Mélanie, Montagnac, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570598/
https://www.ncbi.nlm.nih.gov/pubmed/34739323
http://dx.doi.org/10.1126/sciadv.abf4647