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Novel suction-based in vivo cutaneous DNA transfection platform

This work reports a suction-based cutaneous delivery method for in vivo DNA transfection. Following intradermal Mantoux injection of plasmid DNA in a rat model, a moderate negative pressure is applied to the injection site, a technique similar to Chinese báguàn and Middle Eastern hijama cupping ther...

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Detalles Bibliográficos
Autores principales: Lallow, Emran O., Jhumur, Nandita C., Ahmed, Ijaz, Kudchodkar, Sagar B., Roberts, Christine C., Jeong, Moonsup, Melnik, Juliet M., Park, Sarah H., Muthumani, Kar, Shan, Jerry W., Zahn, Jeffrey D., Shreiber, David I., Singer, Jonathan P., Park, Young K., Maslow, Joel N., Lin, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570601/
https://www.ncbi.nlm.nih.gov/pubmed/34739313
http://dx.doi.org/10.1126/sciadv.abj0611