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Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Angiogenesis and Lung Pathology in a Sheep Model of Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive chronic lung disease characterized by excessive extracellular matrix (ECM) deposition in the parenchyma of the lung. Accompanying the fibrotic remodeling, dysregulated angiogenesis has been observed and implicated in the development and progressio...

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Detalles Bibliográficos
Autores principales: Derseh, Habtamu B., Perera, Kopiyawaththage U. E., Dewage, Sasika N. Vithana, Stent, Andrew, Koumoundouros, Emmanuel, Organ, Louise, Pagel, Charles N., Snibson, Ken J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570673/
https://www.ncbi.nlm.nih.gov/pubmed/34744706
http://dx.doi.org/10.3389/fphar.2021.700902