Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus

Selective neuromodulation using designer receptors exclusively activated by designer drugs (DREADDs) has become an increasingly important research tool, as well as an emerging therapeutic approach. However, the safety profile of DREADD expression is unknown. Here, different titers of adeno-associate...

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Detalles Bibliográficos
Autores principales: Goossens, Marie-Gabrielle, Larsen, Lars Emil, Vergaelen, Marijke, Wadman, Wytse, Van den Haute, Chris, Brackx, Wayra, Proesmans, Silke, Desloovere, Jana, Christiaen, Emma, Craey, Erine, Vanhove, Christian, Vonck, Kristl, Boon, Paul, Raedt, Robrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570686/
https://www.ncbi.nlm.nih.gov/pubmed/34620623
http://dx.doi.org/10.1523/ENEURO.0105-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570686/
https://www.ncbi.nlm.nih.gov/pubmed/34620623
http://dx.doi.org/10.1523/ENEURO.0105-21.2021

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