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Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus
Selective neuromodulation using designer receptors exclusively activated by designer drugs (DREADDs) has become an increasingly important research tool, as well as an emerging therapeutic approach. However, the safety profile of DREADD expression is unknown. Here, different titers of adeno-associate...
Autores principales: | Goossens, Marie-Gabrielle, Larsen, Lars Emil, Vergaelen, Marijke, Wadman, Wytse, Van den Haute, Chris, Brackx, Wayra, Proesmans, Silke, Desloovere, Jana, Christiaen, Emma, Craey, Erine, Vanhove, Christian, Vonck, Kristl, Boon, Paul, Raedt, Robrecht |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570686/ https://www.ncbi.nlm.nih.gov/pubmed/34620623 http://dx.doi.org/10.1523/ENEURO.0105-21.2021 |
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