Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila

Regulation of DNA replication and copy number is necessary to promote genome stability and maintain cell and tissue function. DNA replication is regulated temporally in a process known as replication timing (RT). Rap1-interacting factor 1 (Rif1) is a key regulator of RT and has a critical function i...

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Detalles Bibliográficos
Autores principales: Das, Souradip, Caballero, Madison, Kolesnikova, Tatyana, Zhimulev, Igor, Koren, Amnon, Nordman, Jared
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570783/
https://www.ncbi.nlm.nih.gov/pubmed/34740250
http://dx.doi.org/10.1093/genetics/iyab147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570783/
https://www.ncbi.nlm.nih.gov/pubmed/34740250
http://dx.doi.org/10.1093/genetics/iyab147

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