Severe and Regionally Widespread Increases in Tissue Urea in the Human Brain Represent a Novel Finding of Pathogenic Potential in Parkinson’s Disease Dementia

Widespread elevations in brain urea have, in recent years, been reported in certain types of age-related dementia, notably Alzheimer’s disease (AD) and Huntington’s disease (HD). Urea increases in these diseases are substantive, and approximate in magnitude to levels present in uraemic encephalopath...

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Detalles Bibliográficos
Autores principales: Scholefield, Melissa, Church, Stephanie J., Xu, Jingshu, Patassini, Stefano, Roncaroli, Federico, Hooper, Nigel M., Unwin, Richard D., Cooper, Garth J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571017/
https://www.ncbi.nlm.nih.gov/pubmed/34751215
http://dx.doi.org/10.3389/fnmol.2021.711396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571017/
https://www.ncbi.nlm.nih.gov/pubmed/34751215
http://dx.doi.org/10.3389/fnmol.2021.711396

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