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Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease

Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a significant amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA), European Medicines Agency (EMA), or Worldwide for another indicatio...

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Detalles Bibliográficos
Autores principales: Shityakov, Sergey, Skorb, Ekaterina V., Förster, Carola Y., Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571023/
https://www.ncbi.nlm.nih.gov/pubmed/34751244
http://dx.doi.org/10.3389/fchem.2021.736509